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Modernizing the Pharmaceutical Manufacturing Base
Lawrence Yu
If we used a time machine to transport a pharmaceutical scientist from the 1960s into a current pharmaceutical production plant, it might be surprising to learn that he would already be familiar with most of the processes and production techniques being used. That’s because not much has changed in…
The Quiet After the Storm
Ryan E. Day
Ihave never been accused of being an early adopter of cutting-edge technology. On the other hand, I don’t dance the Luddite jig, either. True to my own type, I hung on to my old M-1A tank, aka a Motorola flip phone, for as long as I could, but was pleased as punch when circumstances led me to…
A Break to Reflect and Unlearn
Kevin Meyer
During  the past few years I’ve been working hard on cultivating positive habits. New habits can be powerful. But habits can also create barriers that limit our perspective, which can hinder kaizen, creativity, and even our knowledge of ourselves. We’ve all found ourselves in the proverbial “rut”…
Use Virtual Conferencing to Eliminate Waste
William A. Levinson
All process activities can be broken down into one of five categories: waiting, handling and setup, inspection, transportation, and transformation. Of these, only transformation of the product adds value. A figure in Frederick Winslow Taylor’s 1911 book, Shop Management makes it clear that, while…
The Three Types of Mentors Every Person Needs
A self-made leader doesn’t make much. I first wrote that statement in my book, Leadership Gold (Thomas Nelson, 2008). Eight years later, I still believe it. After all, I’m not a self-made man; it took a lot of people investing in me to get me where I am today. You may wonder who helped me. Well,…
What We Mean When We Talk About EvGen, Part 1
Rachel E. Sherman, Robert M. Califf
Across the clinical research enterprise, there is a growing awareness of serious shortfalls in the current model for generating the scientific evidence that supports medical product evaluation and clinical care decisions. As a result the FDA seeks to modernize methods and satisfy expectations…
We Need a National Conversation About Sensible Drone Laws
Paul Voss
Not long ago, most Americans could safely ignore congressional deliberations about Federal Aviation Administration (FAA) authority, leaving the details to industry experts and lobbyists. But this time, we may need to fasten our seatbelts and actually read the card in the seat pocket. A bill under…
How Biases Can Ruin Our Decisions
Naveen Khajanchi
Adam Grant, a professor of psychology at Wharton, admitted how wrong he was to pass up on the opportunity to invest in an online startup selling glasses. Because the company didn’t have a functioning website the day before its launch, and because other competitors were already operating in the…
Engine Design Takes a Major Leap Forward
Argonne National Laboratory
The search for a truly revolutionary engine design that can make dramatic gains in efficiency requires deep scientific understanding and tools. Lots and lots of tools. In the past, tools were needed to make prototypes, requiring repeated testing and retrofitting along with a healthy dose of…
Five Ways to Inspire Purposeful Collective Action
Quy Huy
Although it’s bad to ignore a crisis, more serious problems for leaders arise when they try to rouse the collective will to address or prevent organizational emergencies. Heads nod around conference tables as well-laid-out rationales and action plans for strategic change are presented. Months…
Nation Should Implement a Medical Device Evaluation System
Duke University
Evidence on the safety and effectiveness of medical devices is difficult to coordinate and assess, despite the critical role medical devices play in diagnosing and treating patients. A new report from the planning board for a national medical device evaluation system (NMDES) describes how the…
Researchers Develop First Widely Useful Standard for Breast MRI
NIST
Researchers at the National Institute of Standards and Technology (NIST) have developed the first widely useful standard for magnetic resonance imaging (MRI) of the breast, a method used to identify and monitor breast cancer. The NIST instrument—a “phantom”—will help standardize MRIs of breast…
Continuous Improvement Accelerates (and Eases) Growth at Hub Pen
GBMP
Hub Pen Co., located in Braintree, Massachusetts, imports specialty writing instruments and imprints them with company logos and other customized inscriptions. In 2013, the company received a grant for training in lean and continuous improvement, which was delivered by the Greater Boston…
Plotting the Complex Path of Products
MIT News
In March 2011, Leonardo Bonanni was preparing to defend his Ph.D. thesis about Sourcemap, software that lets consumers map every connection of a product supply chain on a digital map, when tragedy struck in Japan. Although the deadly earthquake and tsunami occurred half a world away, the events…
The Art of Managing Dispersed Teams
Knowledge at Wharton
A trained mechanical engineer, Mark Chang found himself “totally uncertain and unprepared” the first time he was called on to hire someone else. “I didn’t even know why I was hired in the first place—what did they like about me?” Chang recalls. “So, how do I go out and look for the next person?”…
Amping Antimicrobial Discovery With Automation
NIST
I n the age-old struggle between humans and microbes, bacteria seem to be regaining the offensive. Only about a dozen classes of chemicals protect us from the myriad pathogens that populate our environment. Numerous agencies have warned that evolved resistance could soon render common antibiotics…
In the Rush for an Agile Workforce, Pulse Surveys Emerge
Gallup
Increasingly dynamic workplaces have made organizational change an everyday reality. Demands for workforce agility require a step up from those commanding—particularly in ongoing measurement and making use of feedback during this breakneck pace of change. There is a definite need for continuous…
Laser-Writing Technique Can Help Manufacturers Create Micro Energy Storage
In the race to design smaller handheld devices and smartphones, a key factor is decreasing the sizes of components. As the demand for thinner and lighter microelectronic devices increases, manufacturers often are limited by how oddly shaped the energy sources must become to make them conform to…
Channeling the Inner Geek
Sandia National Laboratories
Sandia’s Engineering Sciences Center helped mark National Engineers Week with a contest, asking Sandians to complete the following sentence: “You know you’re an engineer when… .” The contest drew dozens of endings for the sentence, and Sandians voted on which they liked best. Barbara Lewis won…
NIST Method May Find Elusive Flaws in Medical Implants and Spacecraft
NIST
Medical implants and spacecraft can suddenly go dead, often for the same reason: cracks in ceramic capacitors, which are devices that store electric charge in electronic circuits. These cracks, at first harmless and often hidden, can start conducting electricity, depleting batteries or shorting…
Why Does It Take So Long to Produce New Car Colors?
Tim Mouw
Detroit recently hosted The North American International Auto Show. It’s an exciting event for consumers who want a sneak peek at what’s on the horizon in the automotive industry: energy efficiency, new gadgets, enhanced comfort, and of course, the latest paint colors and special-effect finishes…
Better Accuracy Out of Thin (or Thick) Air
NIST
NIST scientists have devised and improved a prototype instrument the size of a loaf of bread that can substantially increase the accuracy of length measurements in commerce. Perhaps surprisingly, it does so by achieving the most accurate measure of the refractive index of air reported to date. An…
A Stake in Innovation
Peter Dizikes
Want to encourage innovation? A new study co-authored by an MIT professor finds that little-known state laws called “constituency statutes” have significant effects on the quantity and quality of innovative business actions. The statutes, which allow companies to prioritize the interests of “…
Casting a New Future
Ryan E. Day
Sponsored Content As global competition stiffens, manufacturing sectors of all stripes are embracing emerging technologies in order to meet customer demands. In the realm of metal casting, Pennsylvania-based Effort Foundry is leading the charge by investing in new technology as part of a…
Creativity Is Not an Accident
Scott Berkun
Many of our most popular stories of discovery are portrayed as accidents or matters of luck. We love these stories because they make creativity seem easy and fun. Nevertheless, they are misleading. In a recent New York Times opinion piece titled “How to Cultivate The Art of Serendipity,” author…

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