Twenty years ago, I was introduced to a graphical method for, as it was put to me, “sharing what you see” with others. It was referred to as a material and information flow diagram, or M&I for short.

Given the fact that the FDA probably doesn’t know what it plans to do in 2014, predicting their actions is challenging, to put it mildly.

A kidney transplant is a lifesaving operation—and yet every year in the United States, about 10 percent of donated kidneys go unused, after being rejected by multiple potential recipients.