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Quality Insider

Mettler-Toledo Presents Webinar on Recent USP Changes

Sept. 18, 2012, at 11 a.m. EDT

Published: Tuesday, August 21, 2012 - 10:56

(Mettler-Toledo: Columbus, OH) -- Mettler-Toledo, a leader in the research and development of products and services in the precision instrument industry, has announced an upcoming webinar with special guest presenter Gregory P. Martin, the president of Complectors Consulting and an industry expert in pharmaceutical analytical chemistry. This free educational webinar titled “Recent USP Changes: Regulatory and Quality Aspects of Sample Preparation” will explain the United States Pharmacopeia’s (USP’s) recent changes to General Chapter 841 (Specific Gravity) and proposed changes to Chapter 1251 (Weighing on an Analytical Balance), in more detail. These updates, which describe gravimetric dosing, will affect the way samples and standards are currently prepared.

The webinar will be hosted on Sept. 18, 2012, at 11 a.m. EDT and can be registered for at http://tinyurl.com/cc8okbq.

The USP has recently made revisions that will have a positive effect on the quality of current analytical sample preparation methods. An update to Chapter 841 (Specific Gravity) was published in the March/April 2012 Pharmacopeial Forum 38(2) which states that the use of mass for preparation of solutions is allowed, providing the density is known. This change supports gravimetric addition of the diluent without a need to revalidate the method. The USP is due to post this revision in USP 36-NF 31 Supplement 1 in early 2013. In addition, the USP is proposing an update to Chapter 1251, Weighing on an Analytical Balance. The revision, expected to be published in the September/October 2012 Pharmacopeial Forum and then in USP 36-NF 31 Supplement 2 in 2013, will offer a detailed description of the steps involved in gravimetric dosing for sample and standard preparation.

In this webinar, Gregory P. Martin, a former director of pharmaceutical analytical chemistry at Merck Research Laboratories, who is also chair of the USP expert panels on validation and verification as well as weights and balances, and Joanne Ratcliff, a weighing and sample preparation expert from Mettler-Toledo, will explain how these USP updates will give the industry the opportunity to significantly improve the sample preparation process. The key benefits of a gravimetric approach, including improved accuracy and precision of results, enhanced data tracking and security, and minimized substance and solvent consumption, will be addressed.

The key learning objectives of this webinar include developing an understanding of how changes to the USP will have a positive effect on your current sample preparation process, discovering why the U.S. Food and Drug Administration (FDA) and USP would support gravimetric sample preparation methods, and learning how to incorporate gravimetric methods into an existing workflow to improve quality of results and minimize substance consumption in the laboratory.

This webinar will be of interest to pharmaceutical and regulatory managers and scientists, and experts engaged in or responsible for the preparation of samples and standards for analytical methods, including method validation and development in analytical R&D or quality assurance/quality control laboratories.


About The Author

Mettler-Toledo’s picture


Originally known for weighing technologies, today Mettler-Toledo International Inc. is a recognized leader in the research and development of products and services in communications, optics, robotics, and other technologies as well as software to integrate these technologies into powerful laboratory, industrial, and retail solutions. Mettler-Toledo offers the most comprehensive range of services in the precision instrument industry on a global level. It is a pioneer in the field of automated chemistry and in developing automatic, accurate, dimensioning and data capture technologies for the transportation/logistics industry.