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Tiny Magnetic Beads Could Help to Quickly Detect Pathogens

Findings point to faster way to find bacteria in food, water, and clinical samples

Image courtesy of the researchers
Jennifer Chu
Tue, 09/05/2023 - 12:03
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Getting blood test results can take anywhere from a day to a week, depending on what a test is targeting. The same goes for tests of water pollution and food contamination. And in most cases, the wait time has to do with time-consuming steps in sample processing and analysis.

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Now, MIT engineers have identified a new optical signature in a widely used class of magnetic beads which could be used to quickly detect contaminants in a variety of diagnostic tests. For example, the team showed the signature could be used to detect signs of the food contaminant salmonella.

The so-called “Dynabeads” are microscopic magnetic beads that can be coated with antibodies that bind to target molecules, such as a specific pathogen. Dynabeads are typically used in experiments in which they are mixed into solutions to capture molecules of interest. But from there, scientists have to take additional, time-consuming steps to confirm that the molecules are indeed present and bound to the beads.

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