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Michael Platt


Use Neuroscience to Build ‘Chemistry’

Seven science-based ideas to create a high-performing team

Published: Tuesday, February 28, 2023 - 12:02

It’s a perfect storm. Just as senior leaders have become overwhelmed with demands and crises too numerous and powerful for any one person, a new study from Korn Ferry and Harvard finds that the majority of teams—so vital to business success—are ineffective. Efforts to improve them, centering on “building chemistry,” are based on hypotheses and hunches; leaders have no real, tangible sense of how to encourage and attain true teamwork, defined as a blend of collaboration, coordination, and partnership.

Recent advancements in neuroscience now point to an answer: shared mindset. Linked to improved cooperation, information sharing, and overall team effectiveness, this critical ingredient has a neurobiological basis; when people cooperate well with one another, their patterns of neuronal activity (i.e., engagement of specific areas in the brain) and physiological processes (such as movement and perception) synchronize. A high degree of synchrony has important implications for team success, leading to increased prosocial behavior, subjective liking, empathy, engagement, processing speed, learning, and cooperation. In other words, it’s the secret to shared mindset and chemistry. Neuroscience research suggests that we can act with precision and intention to achieve synchrony in teams.

Action steps

The seven science-based ideas below can be used alone or in combination to encourage and create an all-important shared mindset.

Eye contact

Brain scans show that when people make eye contact, synchrony increases. When they look away, synchrony decreases. Eye contact activates the mirror neuron system and the cerebellum of the people engaged in a social gaze. It helps prepare us to understand the actions and intentions of others. In fact, a study led by Suzanne Dikker and David Poeppel showed how two minutes of sustained eye contact between teachers and students in the classroom resulted in enhanced neural synchrony, higher engagement, and subsequent improvement in performance.

Shared purpose

Identifying the group’s purpose is one way to create common ground that transcends demographic or personal characteristics. By deliberately establishing shared purpose, leaders can maximize inclusivity, collaboration, and success.

Deeper conversations

Wharton Neuroscience Initiative suggests using deep conversation prompt cards that encourage discussion of meaningful, values-based topics, cutting through the standard surface-level chat to create more substantial connections faster.

More time together

Trust and affection tend to increase when you share someone’s company more often. Research from Gallup confirms a relationship between turnover and team performance. When team members feel more interconnected, they have almost 60-percent less turnover and score in the top 20 percent for engagement. Research from MIT-Sloan shows that company-organized social events, such as happy hours and team-building excursions, are associated with higher rates of retention. Neuroscience studies also show that the more time people spend with one another, the greater synchrony they exhibit.

Personal gratitude

Letting someone know how much you appreciate them can increase prosocial feelings on both sides—the person expressing the gratitude gets the same boost in happiness as the person receiving it. As a leader, make a point of expressing gratitude to your team.


Listening to music has been shown to increase oxytocin levels, thereby improving mood, motivation, and the ability to create bonds with others. Whether a meeting is virtual or in-person, team leaders can consider having music playing as people enter the space before a meeting starts.

Find and leverage ‘chemistry creators’

Laboratory research corroborates the existence of chemistry creators and the effect they have on the levels of team synchrony. These people influence the degree of synchrony a team experiences by how much they talk in a group setting. When these people talk, there’s greater inter-brain synchrony across the group.

“It’s interesting to try to figure out what that something is with U2, because we never talk about it.... These fairly able musicians who together become way more than they could ever achieve on their own—that alchemy, there’s something I would love to understand about it that I don’t.”
—Bono in a New York Times interview

How leaders use it

Colleen Maleski, former director for network advancement at Strive Together, a national organization that works to improve outcomes for children “from cradle to career,” uses music to generate better meeting outcomes. This blog post outlines her approach, specific music, and results, showing how “the right music can impact the mood and energy of a room of participants, translating to a greater fervor and enthusiasm for the task at hand—and ideally to achieving the group’s results.”

Matt Richards, associate dean of students and director of athletics at Southern Maine Community College, says his record as the school’s winningest coach is due to his ability to find and encourage chemistry creators—individuals who raise the level of synchrony in a group. A losing season early in his career led him to understand that although he had a talented team and “focused a lot on recruitment, practice preparation, player evaluations, scouting, and film breakdown,” he “never took the time to define what our team was about and mesh personalities.”

The next season, he focused on finding and rewarding chemistry creators, explaining what these key team members do and say, while also discouraging what he terms “energy suckers.” “Along with bolstering actions associated with chemistry creators, you have to be on the lookout for energy-sucking behavior,” Richards says. “When you spot it, correct it immediately.”

First published Jan. 23, 2023, in Knowledge at Wharton. Read the original article here.


About The Author

Michael Platt’s picture

Michael Platt

Michael Platt is a neuroscientist known for asking some of the most challenging questions in 21st-century neuroscience—and conceiving innovative ways to find the answers in the biological mechanisms that underlie decision making in social environments. His expertise in psychology, economics, evolutionary biology, and ethology has enabled him to reach ever-deeper levels of understanding about the neural bases of cognitive behavior. As a Penn Integrates Knowledge (PIK) professor, he has appointments in the Department of Neuroscience in the Perelman School of Medicine, the Department of Psychology in the School of Arts and Sciences, and the Department of Marketing in the Wharton School.