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Thermo Fisher Scientific Inc.

FDA Compliance

Product News: Thermo Fisher Scientific, Multiresidue Analysis of Pesticides

New method enables rapid and accurate identification and quantification of pesticides in rice.

Published: Monday, December 7, 2009 - 15:31

(Thermo Fisher Scientific Inc.: Austin, TX) -- Thermo Fisher Scientific Inc. recently announced a new method that enables rapid and accurate identification and quantification of pesticides in rice. The QuEChERS (quick, easy, cheap, effective, rugged and safe) extraction method takes advantage of the Thermo Scientific ITQ 700 GC-ion trap mass spectrometer and the Thermo Scientific FOCUS GC gas chromatograph to increase speed and improve sample preparation. The application note describing the method, entitled “Multi-residue Pesticide Analysis in Rice by a Modified QuEChERS Extraction and Ion Trap GC/MSn Analysis,” is available for download via the applications focus area at www.thermo.com/gcfoodsafety.

Recently formulated pesticides are smaller in molecular weight than their predecessors and are designed to break down rapidly in the environment. As a result, more careful consideration must be placed on the sample preparation for extraction and the instrument parameters for analysis in order to successfully identify and quantify these compounds in foods. The QuEChERS sample preparation method, which is already shown to simplify the determination of pesticides in fruits, vegetable, grains, and herbs, can now be used to successfully prepare rice extracts before ion trap GC/MSn analysis.

The study was performed by pairing the ITQ 700 with the Thermo Scientific FOCUS GC gas chromatograph to establish the linear ranges, quantitation limits, and detection limits for a list of pesticides that are commonly used on rice crops. Samples were prepared in matrix using the QuEChERS sample preparation method, which involves extraction, clean-up, and solvent exchange processes. The ITQ 700 GC-ion trap MS demonstrated excellent accuracy at low concentrations of 33 pesticide residues analyzed in rice. The optional MSn mode was shown to offer enhanced selectivity over scanning modes such as full scan and selected ion monitoring (SIM). This enables users to identify, confirm, and quantify the existence of pesticides in a single analytical run. In addition, the daily analysis of endrin, DDT, and their breakdown products confirmed the system’s ability to analyze active compounds without the need for continual, expensive, and time-consuming maintenance.

For more information about the Thermo Scientific GC/MS food safety applications, please call (866) 463-6522, e-mail analyze@thermofisher.com.  To download the application note, visit www.thermo.com/gcfoodsafety.

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Thermo Fisher Scientific Inc.

Thermo Fisher Scientific Inc.’s products and services help accelerate the pace of scientific discovery and solve analytical challenges from complex research to routine testing to field applications. Headquartered in Waltham, MA, it serves customers within pharmaceutical and biotech companies, hospitals, clinical diagnostic labs, universities, research institutions, government agencies, and environmental and industrial process control settings. Customers are served through two premier brands: Thermo Scientific—offering high-end analytical instruments, laboratory equipment, software, services, consumables, and reagents to enable integrated laboratory workflow solutions, and Fisher Scientific—providing laboratory equipment, chemicals, supplies, and services used in health care, scientific research, safety, and education.